Can A Virus Cause Obesity?


So what do you know about a virus called Adenovirus-36? Or a virus called SMAM-1? It is common knowledge that they are related to common cool virus. Adenovirus-36 causes eye plus respiratory infections in humans.

What we should learnt recently is these two viruses may cause fattening of animal and human tissue. Research out of Louisiana State College indicates that obesity may be caused by these viruses.

Not all researchers go along with this finding. Steve Bloom, an obesity researcher at Hammersmith Hospital in London flatly refuses to believe that viruses are a common cause of obesity.

Nikhil Durundhar of LSU, who very first showed that both these rogue viruses could make animals put on weight, found that the lab animals infected with all the virus spread it to their competition mates in 12 hours. So obesity could be infectious as well.

Magdalena Passarica isolated the stem cellular material from the fat extracted during the large volume liposuction atlanta. She then infected these tissues with Adrenovirus-36. Not only did the pv cells multiply but also became bloated with fat. She presented her results in September, 2007, Boston at the American Chemical Society. Further more, it is intriguing to note that exposure of human stem cells to other viruses had no such effect.

The study by Dhurundhar and Pasarica involved overweight and non-obese people of both genders in the age group of 29-45. 360 obese people and a hunread forty two thin people participated. Their study also showed that viruses fattened the cells but also decreased the bad cholesterol and triglycerides in the bodies.
If this can be proven without any doubt that this is indeed the case, then we may have a remedy for obesity. There are two ways to do this. Vaccinate against the Adenovirus-36 is one way. Or you can kill it with no- viral drugs. Passarica of LSU proved that Cidofovir, an antiviral drug, is effective anti – dosage to Adrenovirus-36 by experimenting on fatty cells of rats.

The particular obesity is a world wide problem. It really is increasing at an alarming rate among people of all ages, genders, races and countries. When the Body Mass Index (BMI) is greater than 30 kg/square meter in a person, that person can be classified as obese. The formally accepted reasons of obesity are usually genetics, behaviour and endocrine. Up to now the infectious etiology has not been discovered fully. If you want to see more information about coronavirus infections look at the web-page.

Other viruses involved in the unhealthy of animal cells are Dog Distemper Virus, Rous associated Virus -7, Borna Disease virus and a Scrapie Agent.

It was later reported by the same group of researchers from LSU in the International Journal associated with Obesity, January, 2007 that “The in vitro and ex vivo studies show that Ad-36 modulates adipocyte differentiation, leptin production and blood sugar metabolism. Whether such a modulation plays a role in enhanced adipogenesis and consequent adiposity in Ad-36 infected animals or humans needs to be determined”.

In an article “Could Virus Contribute to Weight gain? ” in the same journal, A Vasilakopoulou and C W le Roux (Hammersmith, London), report in April, 2007, “More work is nevertheless required to elucidate the mechanisms associated with weight gain after viral infection. Within the mean time, discounting viruses being a contributing factor to obesity might deprive us of a potential new avenue of investigating and dealing with the ever increasing epidemic of weight problems. Obesity is currently thought of as a way of life disease, but two decades ago so was peptic ulcer disease before the groundbreaking work by Warren plus Marshall on Helicobacter pylori”.

Near to 100 million Americans are affected by weight problems. To alleviate the pain of such large number of people, it is worth while to extend research to find more robust evidence to get viral causes which may lead to remedies other than liposuction.

The study of viral infection as a cause of obesity was done on animals and people. The results were published in highly regarded journals. It is quite clear that infections can not be ruled out as a cause of fattening in humans. But how viruses fatten the cells is still a virgin track to be explored. Once the system is understood, skeptics may be converted. That is how science progresses. We are able to guess what might happen when infections infect cells. They might react with the surface of the cell and increase the volume. Conversely, the viruses may enter the cell and affect the primary and the way energy is invested. Virus may affect a particular organ without causing damage to other internal organs. There are instances in literature exactly where this happened. We may go back to 1916-1917 when a viral outbreak occurred. Constantin von Economo reported a condition that found damage in substantia nigra without any damage to other portions of the brain.

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